Reversing Chronic Colitis.

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ABSTRACT Inflammatory bowel disease (IBD) is a poorly understood chronic immune disorder for which there is no medical cure. Milk and colostrum are rich sources of bioactives with immunomodulatory properties. Here we compared the therapeutic effects of oral delivery of bovine milk-derived iron-saturated lactoferrin (FebLF), angiogenin, osteopontin (OPN), colostrum whey…
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Herpes Simplex Virus HSV-1: A study

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Abstract Immune milk has been developed as a substitute for colostrum and contains a high concentration of IgG antibodies specific to the immunized pathogens. Meanwhile, bovine herpesvirus type-1 (BHV-1) naturally infects cattle worldwide, and its antibody is found in milk. Moreover, BHV-1 glycoprotein K, the major antigen, exhibits substantial homology…
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Colostrum alleviates immune mediated colitis

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Background: Gut-derived bacterial endotoxin is an important cofactor in the pathogenesis of IBD. Regulatory T cells (Tregs) are essential for maintenance of peripheral tolerance and can prevent and alleviate IBD. To determine the immune modulatory effect of anti-LPS enriched hyperimmune colostrum, its ability to induce Tregs and alleviate immune mediated…
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Bovine Colostrum and Murine Lymphoma Cells

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DISCUSSION: Bovine Colostrum and Murine Lymphoma Cells UDP-Ga1NAc:polypeptide N-acetylgalactosaminyltransferase purified to homogeneity from bovine colostrum is a monomer of approximately 70,000 daltons as determined by both SDS-PAGE and gel filtration chromatography. An antibody raised against the purified 70,000-dalton enzyme precipitates the enzyme activity as well as the radiolabeled protein. The difference…
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